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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 30.91
Human Site: S407 Identified Species: 48.57
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 S407 G T P E K P L S D L G L L S Y
Chimpanzee Pan troglodytes XP_508558 546 61795 S440 G T P E K P L S D L G L L S Y
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 T342 P F L F Y V M T E Y D C K G F
Dog Lupus familis XP_540849 546 61797 S440 G T P E K P L S D L G L L S Y
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 S407 G T P E K P L S D L G L L S Y
Rat Rattus norvegicus Q5XI06 458 52614 K358 K P L S D L G K L S Y R S Y W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 Y488 G F D S G R H Y W E V E V G D
Zebra Danio Brachydanio rerio NP_001013327 538 61712 S432 G T P E K P L S D L G L L S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 S435 G S P E K P L S D L G L L S Y
Honey Bee Apis mellifera XP_396552 453 52544 Y353 S D L G L L S Y R S Y W A H T
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 Y358 G L L S Y R S Y W S M A I M K
Sea Urchin Strong. purpuratus XP_786024 440 50807 S339 L S D L G L L S Y R S Y W S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 E345 E G K V G T P E R P L S D L G
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 G345 E K P L S D L G L L S Y R A Y
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 S400 G S P E K P L S D L G L L S Y
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 0 100 N.A. 100 0 N.A. N.A. N.A. 6.6 100 N.A. 93.3 0 6.6 20
P-Site Similarity: 100 100 26.6 100 N.A. 100 6.6 N.A. N.A. N.A. 13.3 100 N.A. 100 0 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 0 26.6 93.3
P-Site Similarity: N.A. N.A. N.A. 0 33.3 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 7 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 7 14 0 7 7 0 0 47 0 7 0 7 0 7 % D
% Glu: 14 0 0 47 0 0 0 7 7 7 0 7 0 0 0 % E
% Phe: 0 14 0 7 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 60 7 0 7 20 0 7 7 0 0 47 0 0 14 7 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 7 7 7 0 47 0 0 7 0 0 0 0 7 0 7 % K
% Leu: 7 7 27 14 7 20 60 0 14 54 7 47 47 7 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 7 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 7 54 0 0 47 7 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 14 0 0 14 7 0 7 7 0 0 % R
% Ser: 7 20 0 20 7 0 14 54 0 20 14 7 7 54 0 % S
% Thr: 0 34 0 0 0 7 0 7 0 0 0 0 0 0 7 % T
% Val: 0 0 0 7 0 7 0 0 0 0 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 14 0 0 7 7 0 7 % W
% Tyr: 0 0 0 0 14 0 0 20 7 7 14 14 0 7 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _